Terminology Service for NFDI4Health
Human gp100 Plasmid DNA Vaccine
Go to external page
http://purl.obolibrary.org/obo/NCIT_C2759
A vaccine consisting of a plasmid DNA encoding the human melanoma-associated antigen gp100. Upon administration, expressed gp100 antigen may stimulate a cytotoxic T cell HLA-A2.1-restricted immune response against tumor cells that express this antigen, resulting in tumor cell lysis. (NCI05) [ ]
Term info
Label
Human gp100 Plasmid DNA Vaccine
Synonyms
- GP100 DNA/VR4951 (Vical)
- Human gp100 Plasmid DNA Vaccine
- gp100 Plasmid DNA
Subsets
NCIT_C128784
Legacy Concept Name
gp100_Plasmid_DNA
NSC Code
702980
PDQ Closed Trial Search ID
419685
PDQ Open Trial Search ID
419685
Preferred Name
Human gp100 Plasmid DNA Vaccine
Semantic Type
Pharmacologic Substance, Gene or Genome
UMLS CUI
C1515637
code
C2759
Term relations
Subclass of:
- DNA Vaccine
- Antineoplastic Vaccine
- Chemical_Or_Drug_Has_Physiologic_Effect some Regulation of Antibody Titer Process
- Chemical_Or_Drug_Has_Physiologic_Effect some T-Cell Activation
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some Cytotoxic T-Lymphocyte
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Gene Regulation Process
- Chemical_Or_Drug_Affects_Abnormal_Cell some Melanoma Cell
- Chemical_Or_Drug_Has_Physiologic_Effect some Immunopotentiation