Terminology Service for NFDI4Health

MART-1 Fowlpox Vaccine

Go to external page http://purl.obolibrary.org/obo/NCIT_C2776


A synthetic cancer vaccine derived from a melanoma-associated antigen, MART-1. Antigenic peptides derived from MART-1 are recognized by CD8+ T lymphocytes and have been used to immunize patients with advanced melanomas; prolonged immunization may result in a reduction in tumor size. Fowlpox virus is an attractive vector because its genome is easy to manipulate and it does not multiply in human tissues. (NCI04) [ ]