Terminology Service for NFDI4Health
pNGVL3-hIL12
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http://purl.obolibrary.org/obo/NCIT_C2791
A plasmid vector encoding interleukin-12 (IL-12) with potential use in the gene therapy of cancer. pNGVL3-hIL12 may induce a high level of IL-12 protein expression during transient transfection of host cells. IL-12 is a proinflammatory cytokine with numerous immunoregulatory functions and may augment host immune responses to tumor cells. (NCI04) [ ]
Term info
Label
pNGVL3-hIL12
Synonyms
- pNGVL3-hIL12
- pNGVL3-hIL12 (IL-12 DNA)
Legacy Concept Name
pNGVL3-hIL12
NSC Code
709933
Preferred Name
pNGVL3-hIL12
Semantic Type
Pharmacologic Substance
UMLS CUI
C1515683
code
C2791
Term relations
Subclass of:
- Antineoplastic Biological Agent
- Gene Therapy Agent
- Gene Transfer or Gene Delivery Agent
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Gene Regulation Process
- Chemical_Or_Drug_Affects_Gene_Product some Interleukin 12 Receptor
- Chemical_Or_Drug_Has_Physiologic_Effect some Cytokine Receptor Activation
- Chemical_Or_Drug_Has_Physiologic_Effect some Immunopotentiation