Terminology Service for NFDI4Health
PR6V10 (ras-12 Asp) Peptide
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http://purl.obolibrary.org/obo/NCIT_C2795
A truncated synthetic form of the oncogene Ras, whose protein product p21 is located in the plasma membrane and transduces growth and differentiation signals from activated receptors to protein kinases within the cell. Because mutated Ras proteins may represent highly specific epitopes for T-cell recognition, PR6V10 (ras-12 Asp) peptide may be used in the vaccine immunotherapy of cancer. (NCI04) [ ]
Term info
Label
PR6V10 (ras-12 Asp) Peptide
Synonyms
- PR6V10 (ras-12 Asp) Peptide
Legacy Concept Name
PR6V10_ras-12_Asp_Peptide
NSC Code
706863
Preferred Name
PR6V10 (ras-12 Asp) Peptide
Semantic Type
Pharmacologic Substance, Amino Acid, Peptide, or Protein
UMLS CUI
C1518811
code
C2795
Term relations
Subclass of:
- Mutated Ras Peptide
- Chemical_Or_Drug_Has_Physiologic_Effect some T-Cell Activation
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some Cytotoxic T-Lymphocyte
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Antigen Sensitization
- Chemical_Or_Drug_Has_Physiologic_Effect some Immunopotentiation