Terminology Service for NFDI4Health

Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C28510


A hybrid gene created by joining portions of two different genes (to produce a new protein) or by joining a gene to a different promoter (to alter or regulate gene transcription). These can be created by chromosomal aberration or by laboratory methods. [ ]

Term info

Label

Fusion Gene

Synonyms
  • Fusion Gene
  • fusion gene
ALT DEFINITION

A gene made by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes. For example, the BCR-ABL gene found in some types of leukemia is a fusion gene. Fusion genes can also be made in the laboratory by combining genes or parts of genes from the same or different organisms.

Gene Encodes Product

Fusion Protein

Legacy Concept Name

Fusion_Gene

Preferred Name

Fusion Gene

Semantic Type

Gene or Genome

UMLS CUI

C1533585

code

C28510

Term relations

Subclass of: