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Therapeutic Tumor Infiltrating Lymphocytes

Go to external page http://purl.obolibrary.org/obo/NCIT_C28699

A preparation of cells, consisting of autologous tumor infiltrating lymphocytes, that are manipulated in vitro and, upon administration in vivo, re-infiltrate the tumor to initiate tumor cell lysis. In vitro, therapeutic tumor-infiltrating lymphocytes (TILs) are isolated from tumor tissue and cultured with lymphokines such as interleukin-2; the therapeutic TILs are then infused into the patient, where, after re-infiltration of the tumor, they may induce lysis of tumor cells and tumor regression. The use of therapeutic TILs is considered a form of adoptive immunotherapy. [ ]

Term info

Label

Therapeutic Tumor Infiltrating Lymphocytes

Synonyms
  • Therapeutic Tumor Infiltrating Lymphocytes
  • Tumor Infiltrating Lymphocyte Therapy
  • Tumor Infiltrating Lymphocytes
Subsets

NCIT_C116978, NCIT_C128784, NCIT_C116977

Display Name

Therapeutic Tumor Infiltrating Lymphocytes

Legacy Concept Name

Therapeutic_Tumor_Infiltrating_Lymphocytes

Preferred Name

Therapeutic Tumor Infiltrating Lymphocytes

Semantic Type

Pharmacologic Substance

UMLS CUI

C1515408

code

C28699