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Falimarev

Go to external page http://purl.obolibrary.org/obo/NCIT_C29316

A cancer vaccine comprised of a recombinant fowlpox viral vector encoding the carcinoembryonic antigen (CEA), MUC-1, a transmembrane glycoprotein secreted by glandular epithelial tissues, and TRICOM, comprised of three co-stimulatory molecule transgenes (B7-1, ICAM-1 and LFA-3). This agent may enhance CEA and MUC-1 presentation to antigen-presenting cells (APC) and may activate a cytotoxic T-cell response against CEA- and MUC-1-expressing tumor cells. [ ]

Term info

Label

Falimarev

Synonyms
  • Falimarev
  • Fowlpox-CEA(D609)-MUC1(L93)-TRICOM Vaccine
  • Fowlpox-CEA-MUC-1-TRICOM
  • PANVAC-F
  • fCEA-MUC-1-TRI
  • falimarev
  • rFowlpox-CEA(D609)/MUC1(L93)/TRICOM Vaccine
  • recombinant fowlpox-CEA-MUC-1-TRICOM vaccine
Subsets

NCIT_C116978, NCIT_C128784, NCIT_C157711, NCIT_C116977, NCIT_C157712

ALT DEFINITION

A cancer vaccine made with a form of a chicken virus that does not cause disease in humans. It is being studied in the treatment of some types of cancer. The virus is changed in the laboratory to make human proteins that may help immune cells in the body kill tumor cells.

CAS Registry

685563-14-8

Display Name

Falimarev

Has Target

http://purl.obolibrary.org/obo/NCIT_C2407, http://purl.obolibrary.org/obo/NCIT_C25159

Legacy Concept Name

rFowlpox-CEA_D609_MUC1_L93_TRICOM

NSC Code

727027

Preferred Name

Falimarev

Semantic Type

Virus, Pharmacologic Substance

UMLS CUI

C1541350

code

C29316