Terminology Service for NFDI4Health
Bence Jones Protein
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http://purl.obolibrary.org/obo/NCIT_C301
Human immunoglobulin kappa and/or lambda light chains detected in their free form in serum or urine samples as a result of overproduction by plasma cells due to neoplastic proliferation. Detection of immunoglobulin light chains in concentrations that exceed that of heavy chains is associated with plasma cell neoplasms. [ ]
Term info
Label
Bence Jones Protein
Synonyms
- Bence Jones Protein
- Bence Jones protein
- Bence-Jones Protein
Subsets
NCIT_C116977, NCIT_C142799
ALT DEFINITION
A small protein made by plasma cells (white blood cells that produce antibodies). It is found in the urine of most people with multiple myeloma (cancer that begins in plasma cells).
Contributing Source
CTRP
Display Name
Bence Jones Protein
Legacy Concept Name
Bence_Jones_Protein
Preferred Name
Bence Jones Protein
Semantic Type
Amino Acid, Peptide, or Protein, Immunologic Factor
UMLS CUI
C0004965
code
C301