Terminology Service for NFDI4Health

Tumor Protein D53

Go to external page http://purl.obolibrary.org/obo/NCIT_C30117


Tumor protein D53 (204 aa, ~22 kDa) is encoded by the human TPD52L1 gene. This protein plays a role in apoptosis. [ ]

Term info

Label

Tumor Protein D53

Synonyms
  • D52-Like 1
  • D53
  • TPD52L1
  • Tumor Protein D52-Like 1
  • Tumor Protein D53
  • hD53
DesignNote

Tumor protein D53 exhibits 52% identity to D52, a coiled-coil domain, and PEST domains. D52, D53, and D54 share significant homology, including a coiled-coil domain indicative of protein-protein interactions. TPD52L1 forms homodimers, or heterodimers with other family members. Like D52, TPD52L1 may be involved in calcium-mediated signal transduction and cell proliferation.

Legacy Concept Name

Tumor_Protein-D52-Like-1_Protein

OMIM Number

604069

Preferred Name

Tumor Protein D53

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q16890

UMLS CUI

C1314855

code

C30117