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Progonadoliberin-1

Go to external page http://purl.obolibrary.org/obo/NCIT_C38492

Progonadoliberin-1 (92 aa, ~10 kDa) is encoded by the human GNRH1 gene. This protein plays a role in regulating the secretion of both luteinizing and follicle-stimulating hormones (LH and FSH, respectively). [ ]

Term info

Label

Progonadoliberin-1

Synonyms
  • GNRH1
  • Progonadoliberin 1
  • Progonadoliberin I
  • Progonadoliberin-1
DesignNote

Progonadoliberin-1 is cleaved into 2 active peptides comprised of either amino acid residues 24-33, which is called gonadoliberin-1 (gonadoliberin I; gonadorelin; gonadotropin-releasing hormone I; GnRH-I; luliberin I; luteinizing hormone-releasing hormone I; LH-RH I; prolactin release-inhibiting factor; PIF), or residues 37-92, which is called GnRH-associated peptide 1 (GnRH-associated peptide I). (UniProt)

Legacy Concept Name

Gonadotrophin_Releasing_Hormone-1

OMIM Number

152760

Preferred Name

Progonadoliberin-1

Semantic Type

Hormone, Amino Acid, Peptide, or Protein

Swiss Prot

P01148

UMLS CUI

C1521753

code

C38492