Terminology Service for NFDI4Health

Progonadoliberin-2

Go to external page http://purl.obolibrary.org/obo/NCIT_C38494


Progonadoliberin-2 (120 aa, ~13 kDa) is encoded by the human GNRH2 gene. This protein is involved in the regulation of luteinizing hormone and follicle-stimulating hormone secretion. [ ]

Term info

Label

Progonadoliberin-2

Synonyms
  • GNRH2
  • Progonadoliberin 2
  • Progonadoliberin II
  • Progonadoliberin-2
DesignNote

Progonadoliberin-2 is cleaved into 2 active peptides comprised of either amino acid residues 24-33, which is called gonadoliberin-2 (gonadoliberin II; gonadorelin; gonadotropin-releasing hormone II; GnRH-II; luliberin II; luteinizing hormone-releasing hormone II; LH-RH II), or residues 37-120, which is called GnRH-associated peptide 2 (GnRH-associated peptide II). (UniProt)

Legacy Concept Name

Gonadotrophin_Releasing_Hormone-2

OMIM Number

602352

Preferred Name

Progonadoliberin-2

Semantic Type

Hormone, Amino Acid, Peptide, or Protein

Swiss Prot

O43555

UMLS CUI

C1531431

code

C38494