Interleukin 12 Receptor
Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain (IL12RB2), each a type I transmembrane disulfide-linked dimer/oligomer protein containing 5 FNIII domains, a box 1 motif required for JAK interaction/activation, and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. Involved in IL12 signal transduction, IL12RB1 and IL12RB2 oligomers act as low affinity IL12 receptors. (NCI) [ ]
Term info
Interleukin 12 Receptor
- High Affinity Interleukin 12 Receptor
- High Affinity Interleukin 12 Receptor Beta
- IL-12R
- IL12R
- Interleukin 12 Receptor
- Interleukin 12 Receptor Beta
- Interleukin-12 Receptor
Interleukin-12_Receptor
Interleukin 12 Receptor
Amino Acid, Peptide, or Protein, Receptor
C0255732
C38915