Terminology Service for NFDI4Health

CYP2D6*2N Allele

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Human CYP2D6*2N allele, a variant form of the CYP2D6 wild-type allele, is approximately 4 kb in length and encodes cytochrome P450 2D6 protein. Amplification of the CYP2D6 gene (up to 12 copies) produces the CYP2D6*2N allele. The enzymatic activity of the protein encoded by this allele is not significantly different from the protein product of the wild-type allele. However, individuals who carry this allele exhibit an ultra-rapid metabolizer phenotype. [ ]

Term info

Label

CYP2D6*2N Allele

Synonyms
  • CYP2D6*2N Allele
  • CYP2D6*2XN
  • Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*2N Allele
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Ethnicity Association: Asian; African American; Black African; Caucasian; Middle Eastern

Display Name

CYP2D6*2N Allele

Gene Encodes Product

Cytochrome P450 2D6

Legacy Concept Name

CYP2D6_2N_Allele

OMIM Number

124030

Preferred Name

CYP2D6*2N Allele

Semantic Type

Gene or Genome

UMLS CUI

C1707219

code

C45619