CYP2D6*2N Allele
Human CYP2D6*2N allele, a variant form of the CYP2D6 wild-type allele, is approximately 4 kb in length and encodes cytochrome P450 2D6 protein. Amplification of the CYP2D6 gene (up to 12 copies) produces the CYP2D6*2N allele. The enzymatic activity of the protein encoded by this allele is not significantly different from the protein product of the wild-type allele. However, individuals who carry this allele exhibit an ultra-rapid metabolizer phenotype. [ ]
Term info
CYP2D6*2N Allele
- CYP2D6*2N Allele
- CYP2D6*2XN
- Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*2N Allele
NCIT_C116977, NCIT_C142800, NCIT_C142799
CTRP
Ethnicity Association: Asian; African American; Black African; Caucasian; Middle Eastern
CYP2D6*2N Allele
NM_000106
Cytochrome P450 2D6
CYP2D6_2N_Allele
124030
CYP2D6*2N Allele
Gene or Genome
C1707219
C45619