CYP2D6*38 Allele
Human CYP2D6*38 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*38 protein. The CYP2D6*38 allele exhibits a four nucleotide deletion (g.2587delGACT) that results in a frameshift during protein coding. This alteration abolishes the enzymatic activity of the cytochrome P450 2D6*38 protein. [ ]
Term info
CYP2D6*38 Allele
- CYP2D6*38
- CYP2D6*38 Allele
- CYP2D6, N2
- CYP2D6, g.2587delGACT
- Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*38 Allele
NCIT_C116977, NCIT_C142800, NCIT_C142799
CTRP
CYP2D6*38 Allele
NM_000106
CYP2D6_38_Allele
124030
CYP2D6*38 Allele
9918137
Gene or Genome
C1707221
C46056
Term relations
- CYP2D6 Gene
- Allele_Has_Abnormality some Frameshift Mutation
- Allele_Plays_Altered_Role_In_Process some Drug Metabolism
- Allele_In_Chromosomal_Location some 22q13.1
- Allele_Plays_Altered_Role_In_Process some Xenobiotic Metabolism
- Allele_Has_Abnormality some Deletion Mutation
- Allele_Has_Activity some Absence of Biochemical Activity