Terminology Service for NFDI4Health
Breast Carcinoma
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http://purl.obolibrary.org/obo/NCIT_C4872
A carcinoma arising from the breast, most commonly the terminal ductal-lobular unit. It is the most common malignant tumor in females. Risk factors include country of birth, family history, menstrual and reproductive history, fibrocystic disease and epithelial hyperplasia, exogenous estrogens, contraceptive agents, and ionizing radiation. The vast majority of breast carcinomas are adenocarcinomas (ductal or lobular). Breast carcinoma spreads by direct invasion, by the lymphatic route, and by the blood vessel route. The most common site of lymph node involvement is the axilla. [ ]
Term info
Label
Breast Carcinoma
Synonyms
- Breast Cancer
- Breast Carcinoma
- Breast cancer, NOS
- Cancer of Breast
- Cancer of the Breast
- Cancer, Breast
- Carcinoma of Breast
- Carcinoma of the Breast
- Mammary Carcinoma
- breast cancer
Subsets
NCIT_C126659, NCIT_C118464, NCIT_C118168, NCIT_C102905, NCIT_C138188, NCIT_C138190, NCIT_C62596, NCIT_C90259, NCIT_C103042, NCIT_C158035, NCIT_C158520, NCIT_C156966, NCIT_C54450, NCIT_C156952, NCIT_C116977
ALT DEFINITION
Cancer that forms in tissues of the breast, usually the ducts (tubes that carry milk to the nipple) and lobules (glands that make milk). It occurs in both men and women, although male breast cancer is rare., A malignant neoplasm that develops or arises in breast tissue.
Contributing Source
CTRP, FDA, CTEP, MedDRA, NICHD, CPTAC
Display Name
Breast Carcinoma
FDA Table
Patient Code (Appendix B)
Has CDRH Parent
http://purl.obolibrary.org/obo/NCIT_C9305
Has NICHD Parent
http://purl.obolibrary.org/obo/NCIT_C9305
Legacy Concept Name
Breast_Carcinoma
Maps To
Breast cancer, Breast Cancer
NICHD Hierarchy Term
Breast Cancer
Neoplasm Has Special Category
http://purl.obolibrary.org/obo/NCIT_C9292
Neoplastic Status
Malignant
Preferred Name
Breast Carcinoma
Semantic Type
Neoplastic Process
UMLS CUI
C0678222
code
C4872
Term relations
Equivalent to:
- Malignant Breast Neoplasm and Carcinoma and Disease_Has_Primary_Anatomic_Site some Breast and Disease_Has_Normal_Tissue_Origin some Mammary Epithelium
Related from:
Gene_Associated_With_Disease
- MIR27B Gene
- ATM Gene
- STK11 Gene
- PDZK1IP1 Gene
- CHKA Gene
- TPD52L1 Gene
- TPD52 Gene
- PTK6 Gene
- TAP1 Gene
- MIR27A Gene
- MIR21 Gene
- MIR127 Gene
- MIR126 Gene
- MIRLET7A3 Gene
- MIRLET7A1 Gene
- MIR20A Gene
- MIR7-3 Gene
- MIR17 Gene
- MIR7-2 Gene
- MIR7-1 Gene
- MIR222 Gene
- MIR124-1 Gene
- MIR335 Gene
- MIR520C Gene
- MIR516A2 Gene
- MIR516B1 Gene
- MIR510 Gene
- MIR516A1 Gene
- MIR451A Gene
- MIR429 Gene
- MIR141 Gene
- MIR155 Gene
- MIR146A Gene
- MIR210 Gene
- MIR206 Gene
- MIR10B Gene
- MIR214 Gene
- MIR200B Gene
- MIR205 Gene
- MIR200A Gene
- MIR146B Gene
- MIR125A Gene
- MIR204 Gene
- MIR200C Gene
- TP53 Gene
- TSG101 Gene
- TARP Gene
- RB1CC1 Gene
- PPM1D Gene
- WNT10B Gene
- WNT3 Gene
- BRCATA Gene
- HMGA1 Gene
- CST6 Gene
- CDH5 Gene
- CDH13 Gene
- FGFR4 Gene
- AGR2 Gene
- APPBP2 Gene
- TRERF1 Gene
- KISS1 Gene
- BCAR1 Gene
- AXIN2 Gene
- BCAR3 Gene
- BCAS1 Gene
- CHMP2A Gene
- BRCA3 Gene
- BCAS2 Gene
- BCAS3 Gene
- BCAS4 Gene
- BRCD1 Gene
- ANKRD30A Gene
- BRMS1 Gene
- CLCA2 Gene
- HYOU1 Gene
- ADAM11 Gene
- TSPAN32 Gene
- CASC3 Gene
- CALML4 Gene
- SNCG Gene
- S100A2 Gene
- TFF1 Gene
- RAD54L Gene
- TSSC4 Gene
- NOVA1 Gene
- CTSD Gene
Gene_Product_Malfunction_Associated_With_Disease
- Protein TSSC4
- WAP Four-Disulfide Core Domain Protein 1
- Tetraspanin-32
- G Antigen Family D Member 3
- Breast Carcinoma-Amplified Sequence 4
- Breast Carcinoma-Amplified Sequence 3
- Breast Carcinoma-Amplified Sequence 1
- Anterior Gradient Protein 2 Homolog
- Metastasis-Suppressor KiSS-1
- Transforming Acidic Coiled-Coil-Containing Protein 1
- T-Cell Receptor Gamma Chain Alternative Reading Frame Protein Isoform 1
- RB1-Inducible Coiled-Coil Protein 1