Terminology Service for NFDI4Health

Recombinant Interferon Beta

Go to external page http://purl.obolibrary.org/obo/NCIT_C495


A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. (NCI05) [ ]

Term info

Label

Recombinant Interferon Beta

Synonyms
  • Beta Interferon
  • Betantrone
  • Feron
  • Human Interferon Beta
  • Interferon Beta
  • Interferon, Beta
  • Interferon-B
  • Interferon-beta
  • Naferon
  • Recombinant Interferon Beta
Subsets

NCIT_C116978, NCIT_C128784, NCIT_C116977, NCIT_C157711, NCIT_C157712

Accepted Therapeutic Use For

multiple sclerosis

CAS Registry

77238-31-4

Display Name

Recombinant Interferon Beta

Is Related To Endogenous Product

http://purl.obolibrary.org/obo/NCIT_C20495

Legacy Concept Name

Therapeutic_Interferon_Beta

NSC Code

373361, 658933

Preferred Name

Recombinant Interferon Beta

Semantic Type

Pharmacologic Substance, Amino Acid, Peptide, or Protein

UMLS CUI

C0015980

code

C495