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Folate Antagonist

http://purl.obolibrary.org/obo/NCIT_C511

A compound with a chemical structure similar to folic acid. Folate antagonists inhibit one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. [ ]

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Term info

Label

Folate Antagonist

Synonyms

Antifolates
Folate Analog
Folate Antagonist
Folate Inhibitors
Folic Acid Analog
Folic Acid Antagonist
Folic Acid Antagonists
Folic Acid Inhibitors
antifolate
folate antagonist

ALT DEFINITION

A substance that blocks the activity of folic acid. Folate antagonists are used to treat cancer.

Legacy Concept Name

Folate_Antagonist

Preferred Name

Folate Antagonist

Semantic Type

Chemical Viewed Functionally

UMLS CUI

C0016411

code

C511

Term relations

Subclass of:

Antimetabolite