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HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C62757

HLA class II histocompatibility antigen, DRB1-4 beta chain protein (266 aa, ~30 kDa) is encoded by the human HLA-DRB1 gene. This protein is involved in both antigen presentation to regulatory T cells and in the immune response. The antigen is frequently typed for bone marrow and kidney transplantation procedures. [ ]

Term info

Label

HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein

Synonyms
  • DR-4
  • DR4
  • HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain
  • HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein
  • HLA-DR4
  • HLA-DR4 Antigen
  • MHC Class I Antigen DRB1*4
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

ALT DEFINITION

A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of DR4 on cancer cells may kill more cells.

Display Name

HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein

Legacy Concept Name

HLA_Class_II_Histocompatibility_Antigen_DRB1-4_Beta_Chain_Protein

OMIM Number

142857

Preferred Name

HLA Class II Histocompatibility Antigen, DRB1-4 Beta Chain Protein

Semantic Type

Amino Acid, Peptide, or Protein, Immunologic Factor

Swiss Prot

P13760

UMLS CUI

C1881023

code

C62757