WT1 Analog Peptide Vaccine
A peptide vaccine comprised of an epitope of human Wilms tumor 1 (WT-1) with potential antineoplastic activity. WT-1, a transcription factor, is overexpressed in most types of leukemia and in some solid cancers. Vaccination with the WT-1 analog peptide vaccine may induce a cytotoxic T-lymphocyte (CTL) response against WT-1 expressing cells, resulting in cell lysis and inhibition of cancer cell proliferation. [ ]
Term info
WT1 Analog Peptide Vaccine
- WT-1 vax
- WT1 Analog Peptide Vaccine
NCIT_C116978, NCIT_C128784, NCIT_C116977
CTRP
WT1 Analog Peptide Vaccine
WT1_Analog_Peptide_Vaccine
518351
518351
WT1 Analog Peptide Vaccine
Pharmacologic Substance, Amino Acid, Peptide, or Protein
C1831984
C64635
Term relations
- Antineoplastic Vaccine
- Peptide Vaccine
- Chemical_Or_Drug_Has_Physiologic_Effect some T-Cell Activation
- Chemical_Or_Drug_Affects_Cell_Type_Or_Tissue some Cytotoxic T-Lymphocyte
- Chemical_Or_Drug_Has_Mechanism_Of_Action some Antigen Sensitization
- Chemical_Or_Drug_Has_Physiologic_Effect some Immunopotentiation