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N-Telopeptide

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This polypeptide is comprised of the amino terminal portions of fibrillar collagen, which are not part of the triple helical structure. Bone resorption of type I collagen by osteoclasts results in the release of this peptide. Thus, this polypeptide is utilized as a biomarker for bone loss. [ ]

Term info

Label

N-Telopeptide

Synonyms
  • Collagen Cross-Linked N-Telopeptide
  • N-Telopeptide
  • N-Terminal Type I Collagen Cross-Linked
  • NTx
  • Type I Collagen Cross-Linked N-Telopeptide
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Triple helical collagen is constructed from more than one gene product; thus, N-telopeptides arise from heterogeneous sources.

Display Name

N-Telopeptide

Legacy Concept Name

N-Telopeptide

Preferred Name

N-Telopeptide

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C1291125

code

C68563