Terminology Service for NFDI4Health
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Mucin-16

Go to external page http://purl.obolibrary.org/obo/NCIT_C71020

Mucin-16 (22152 aa, ~2353 kDa) is encoded by the human MUC16 gene. This protein may be involved in both cellular adhesion and the lubrication of mucosal surfaces. [ ]

Term info

Label

Mucin-16

Synonyms
  • CA-125
  • MUC16
  • Mucin 16
  • Mucin-16
  • Ovarian Cancer-Related Tumor Marker CA125
  • Ovarian Carcinoma Antigen CA125
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Mucin-16 is a glycoprotein that is synthesized with a single transmembrane domain, and can be proteolytically released from the membrane after intracellular phosphorylation occurs. This protein has been identified as the CA-125 ovarian cancer antigen, which is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer. This marker cannot detect early ovarian cancer and is not specific enough to be used for population screening. (SwissProt)

Display Name

Mucin-16

OMIM Number

606154

Preferred Name

Mucin-16

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q8WXI7

UMLS CUI

C2347296

code

C71020