Terminology Service for NFDI4Health
Myeloperoxidase
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http://purl.obolibrary.org/obo/NCIT_C71145
Myeloperoxidase (745 aa, ~84 kDa) is encoded by the human MPO gene. This protein is involved in the regulation of the innate host defense through the production of hypohalous acids. [ ]
Term info
Label
Myeloperoxidase
Synonyms
- EC 1.11.1.7
- MPO
- MYELOPEROXIDASE
- Myeloperoxidase
Subsets
NCIT_C63923, NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP, FDA
DesignNote
Myeloperoxidase is synthesized as a single chain precursor that is cleaved into a light and heavy chain. The mature enzyme is a tetramer composed of 2 light chains and 2 heavy chains. (EntrezGene)
Display Name
Myeloperoxidase
FDA UNII Code
JQZ6YM58U5
Legacy Concept Name
Myeloperoxidase
OMIM Number
606989
Preferred Name
Myeloperoxidase
Semantic Type
Amino Acid, Peptide, or Protein, Enzyme
Swiss Prot
P05164
UMLS CUI
C0027021
code
C71145
Term relations
Subclass of:
- Oxidoreductase
- Gene_Product_Plays_Role_In_Biological_Process some Host Defense Mechanism
- Gene_Product_Plays_Role_In_Biological_Process some Antimicrobial Effect
- Gene_Product_Plays_Role_In_Biological_Process some Oxidation
- Gene_Product_Has_Organism_Source some Human
- Gene_Product_Encoded_By_Gene some MPO Gene