Terminology Service for NFDI4Health
HLA-DP Antigen
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http://purl.obolibrary.org/obo/NCIT_C71274
HLA-DP antigen is a class of glycoproteins that consist of dimers of alpha and beta subunits, which are encoded by the polymorphic human genes HLA-DPA1 and HLA-DPB1, respectively. This protein complex is expressed primarily in lymphoid cells and function to present antigens for CD4+ T lymphocytes. [ ]
Term info
Label
HLA-DP Antigen
Synonyms
- HLA-DP
- HLA-DP Antigen
Legacy Concept Name
HLA-DP_Antigen
Preferred Name
HLA-DP Antigen
Semantic Type
Amino Acid, Peptide, or Protein, Immunologic Factor
UMLS CUI
C0019759
code
C71274
Term relations
Subclass of:
- MHC Class II Protein
- Gene_Product_Has_Chemical_Classification some Transmembrane Protein
- Gene_Product_Plays_Role_In_Biological_Process some Immune Response Process
- Gene_Product_Has_Structural_Domain_Or_Motif some Cytoplasmic Domain
- Gene_Product_Has_Chemical_Classification some Glycoprotein
- Gene_Product_Plays_Role_In_Biological_Process some Antigen Presentation
- Gene_Product_Has_Associated_Anatomy some Plasma Membrane
- Gene_Product_Has_Organism_Source some Human
- Gene_Product_Has_Structural_Domain_Or_Motif some Extracellular Domain
- Gene_Product_Has_Structural_Domain_Or_Motif some Transmembrane Domain