Safingol Hydrochloride
The hydrochloride salt of a saturated derivative of sphingosine. As an inhibitor of protein kinase C (PKC), safingol competitively binds to the regulatory phorbol-binding domain of PKC, a kinase involved in tumorigenesis. This agent has been shown to act synergistically with other chemotherapeutic agents and may potentiate chemotherapy drug-induced apoptosis in vitro and in vivo. [ ]
Term info
Safingol Hydrochloride
- (2S,3S)-2-Amino-1,3-Octadecanediol Hydrochloride
- 1,3-Octadecanediol, 2-amino-, Hydrochloride, (S-(R*,R*))-
- SAFINGOL HYDROCHLORIDE
- SPC-100271
- Safingol HCl
- Safingol Hydrochloride
NCIT_C63923
139755-79-6
C18H39NO2.HCl
30MA50WJ4N
http://purl.obolibrary.org/obo/NCIT_C1568
Safingol_Hydrochloride
Safingol Hydrochloride
Pharmacologic Substance, Organic Chemical
C0888599
C80327