Terminology Service for NFDI4Health
Vasculostatin
Go to external page
http://purl.obolibrary.org/obo/NCIT_C83192
Vasculostatin (899 aa, ~120 kDa) is encoded by the human BAI1 gene. This protein fragment is involved in the regulation of tumor angiogenesis. [ ]
Term info
Label
Vasculostatin
Synonyms
- Vasculostatin
- Vstat120
DesignNote
Vasculostatin is an extracellular domain in brain-specific angiogenesis inhibitor 1 that is released by cleavage at a conserved G-protein-coupled receptor proteolytic cleavage site at a serine at amino acid 927. The released molecule has an RGD integrin binding motif and five thrombospondin type 1 repeats. (Oncogene (2005) 24, 3632-3642.)
Legacy Concept Name
Vasculostatin_from_BAI1
Preferred Name
Vasculostatin
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C1336952
code
C83192