Terminology Service for NFDI4Health

RNA-Induced Silencing Complex

Go to external page http://purl.obolibrary.org/obo/NCIT_C84404


A RNA-protein complex that catalyzes facilitates the association of either a microRNA or a small interfering RNA with its complementary coding RNA and then degrades the targeted coding RNA molecule. [ ]

Term info

Label

RNA-Induced Silencing Complex

Synonyms
  • RISC
  • RNA-Induced Silencing Complex
DesignNote

This complex is active in both miRNA-dependent gene regulation, and the response to viral infection.

Preferred Name

RNA-Induced Silencing Complex

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C1099355

code

C84404