RNA-Induced Silencing Complex
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http://purl.obolibrary.org/obo/NCIT_C84404
A RNA-protein complex that catalyzes facilitates the association of either a microRNA or a small interfering RNA with its complementary coding RNA and then degrades the targeted coding RNA molecule. [ ]
Term info
Label
RNA-Induced Silencing Complex
Synonyms
- RISC
- RNA-Induced Silencing Complex
DesignNote
This complex is active in both miRNA-dependent gene regulation, and the response to viral infection.
Preferred Name
RNA-Induced Silencing Complex
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C1099355
code
C84404
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Plays_Role_In_Biological_Process some RNA Degradation
- Gene_Product_Plays_Role_In_Biological_Process some RNA Interference
- Gene_Product_Plays_Role_In_Biological_Process some Translational Regulation
- Gene_Product_Is_Element_In_Pathway some Double Stranded RNA Biosynthesis Pathway