Terminology Service for NFDI4Health
JSON

Malignant Neoplasm

Go to external page http://purl.obolibrary.org/obo/NCIT_C9305

A tumor composed of atypical neoplastic, often pleomorphic cells that invade other tissues. Malignant neoplasms often metastasize to distant anatomic sites and may recur after excision. The most common malignant neoplasms are carcinomas (adenocarcinomas or squamous cell carcinomas), Hodgkin and non-Hodgkin lymphomas, leukemias, melanomas, and sarcomas. [ ]

Term info

Label

Malignant Neoplasm

Synonyms
  • CA
  • Cancer
  • Malignancy
  • Malignant Growth
  • Malignant Neoplasm
  • Malignant Neoplastic Disease
  • Malignant Tumor
  • NEOPLASM, MALIGNANT
  • cancer
  • malignancy
Subsets

NCIT_C99147, NCIT_C118464, NCIT_C118168, oncotree_slim, NCIT_C77526, NCIT_C88025, NCIT_C90259, NCIT_C62596, NCIT_C158034, NCIT_C61410, NCIT_C158520, NCIT_C19752, NCIT_C156966, NCIT_C156954, NCIT_C54450, NCIT_C156953, NCIT_C156952, NCIT_C116977

ALT DEFINITION

A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Malignant cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of malignancy. Carcinoma is a malignancy that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a malignancy that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a malignancy that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are malignancies that begin in the cells of the immune system. Central nervous system cancers are malignancies that begin in the tissues of the brain and spinal cord., Uncontrolled growth of abnormal cells with potential for metastatic spread., A general term for autonomous tissue growth exhibiting morphologic features of malignancy (e.g. severe atypia, nuclear pleomorphism, tumor cell necrosis, abnormal mitoses, tissue invasiveness) and for which the transformed cell type has not been specifically identified.

Contributing Source

CTRP, FDA, MedDRA, CDISC, NICHD, CPTAC

Display Name

Malignant Neoplasm

Has CDRH Parent

http://purl.obolibrary.org/obo/NCIT_C54450

Has NICHD Parent

http://purl.obolibrary.org/obo/NCIT_C3262

ICD-O-3 Code

8000/3

Legacy Concept Name

Malignant_Neoplasm

Maps To

Malignant neoplasm, unspecified, Malignant neoplasm of other specified sites, Malignant neoplasm, primary site unknown, so stated, Malignancy, Malignant neoplasm of other and ill-defined sites: Overlapping lesion of other and ill-defined sites, 8000/3, Malignant neoplasm of other and ill-defined sites, Other malignant neoplasm of unspecified site, Malignant neoplasm of other and ill-defined sites: Lower limb, Neoplasm, malignant, Malignant neoplasm, without specification of site, Malignant neoplasm without specification of site, Cancer, Tumor, malignant, NOS, Unclassified tumor, malignant

Neoplastic Status

Malignant

Preferred Name

Malignant Neoplasm

Semantic Type

Neoplastic Process

UMLS CUI

C0006826

code

C9305