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SLAM Family Member 7

Go to external page http://purl.obolibrary.org/obo/NCIT_C95308

SLAM family member 7 (335 aa, ~37 kDa) is encoded by the human SLAMF7 gene. This protein is involved in signal transduction that promotes the activation of natural killer cells. [ ]

Term info

Label

SLAM Family Member 7

Synonyms
  • CD Antigen CD319
  • CD2 Subset 1
  • CD2-Like Receptor Activating Cytotoxic Cells
  • CD2-Like Receptor-Activating Cytotoxic Cells
  • CD319
  • CD319 Antigen
  • CRACC
  • Membrane Protein FOAP-12
  • Novel Ly9
  • Protein 19A
  • SLAM Family Member 7
  • SLAMF7
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

There are 3 isoforms of SLAM family member 7 that result from alternative splicing. SLAM family member 7 isoform 3 is known as 19A24 protein and does not have the same natural killer cell activation activity as the canonical isoform 1. (UniProt), SLAM family member 7 may be a target for elotuzumab in the treatment of multiple myeloma.

Display Name

SLAM Family Member 7

OMIM Number

606625

Preferred Name

SLAM Family Member 7

Semantic Type

Amino Acid, Peptide, or Protein

Swiss Prot

Q9NQ25

UMLS CUI

C1099412

code

C95308