Terminology Service for NFDI4Health

NEDD8 Activating Enzyme

Go to external page http://purl.obolibrary.org/obo/NCIT_C95815


NEDD8 activating enzyme is comprised of NEDD8-activating enzyme E1 regulatory subunit and NEDD8-activating enzyme E1 catalytic subunit. This protein complex modifies the C-terminus of NEDD8 to regulate protein neddylation, ubiquitination and catabolism. [ ]

Term info

Label

NEDD8 Activating Enzyme

Synonyms
  • NAE
  • NEDD8 Activating E1 Enzyme
  • NEDD8 Activating Enzyme
  • NEDD8-Activating Enzyme
  • UBA3-NAE1 E1 Enzyme
Preferred Name

NEDD8 Activating Enzyme

Semantic Type

Amino Acid, Peptide, or Protein, Enzyme

UMLS CUI

C3272370

code

C95815