Terminology Service for NFDI4Health
mTORC1
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http://purl.obolibrary.org/obo/NCIT_C96314
A protein complex that is involved in the both serine/threonine phosphorylation and the regulation of protein synthesis in response to cellular stress. [ ]
Term info
Label
mTORC1
Synonyms
- Raptor-mTOR
- Raptor/TORC1
- TOR Complex 1
- TORC1
- Target of Rapamycin Complex 1
- mTOR Complex 1
- mTORC1
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
mTORC1 is comprised of serine/threonine-protein kinase mTOR, regulatory-associated protein of mTOR, proline-rich AKT1 substrate 1 and target of rapamycin complex subunit LST8. (UniProt), The activity of this complex is inhibited by rapamycin.
Display Name
mTORC1
Preferred Name
mTORC1
Semantic Type
Amino Acid, Peptide, or Protein, Enzyme
UMLS CUI
C3888046
code
C96314
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Is_Element_In_Pathway some Hepatocyte Growth Factor Receptor Signaling Pathway PID
- Gene_Product_Plays_Role_In_Biological_Process some Serine/Threonine Phosphorylation
- Gene_Product_Plays_Role_In_Biological_Process some Translational Activation
- Gene_Product_Is_Element_In_Pathway some mTOR Signaling Pathway PID