Terminology Service for NFDI4Health
mTORC2
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http://purl.obolibrary.org/obo/NCIT_C96315
A protein complex that is involved in both serine/threonine phosphorylation and cytoskeleton remodeling in response to cellular stress. [ ]
Term info
Label
mTORC2
Synonyms
- Rictor-mTOR
- Rictor/TORC2
- TOR Complex 2
- TORC2
- Target of Rapamycin Complex 2
- mTOR Complex 2
- mTORC2
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
mTORC2 is comprised of serine/threonine-protein kinase mTOR, rapamycin-insensitive companion of mTOR, proline-rich protein 5, target of rapamycin complex 2 subunit MAPKAP1 and target of rapamycin complex subunit LST8. (UniProt)
Display Name
mTORC2
Preferred Name
mTORC2
Semantic Type
Amino Acid, Peptide, or Protein, Enzyme
UMLS CUI
C3152112
code
C96315
Term relations
Subclass of:
- Protein or Riboprotein Complex
- Gene_Product_Is_Element_In_Pathway some PI3K/AKT1 Signaling Pathway
- Gene_Product_Is_Element_In_Pathway some CXCR4-Mediated Signaling Pathway
- Gene_Product_Plays_Role_In_Biological_Process some Serine/Threonine Phosphorylation
- Gene_Product_Is_Element_In_Pathway some CXCR3-Mediated Signaling Pathway
- Gene_Product_Is_Element_In_Pathway some Epidermal Growth Factor Receptor Downstream Signaling Pathway
- Gene_Product_Is_Element_In_Pathway some mTOR Signaling Pathway PID