Terminology Service for NFDI4Health
JSON

Paclitaxel Ceribate

Go to external page http://purl.obolibrary.org/obo/NCIT_C96934

The ceribate ester form of paclitaxel, a compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to and stabilizes tubulin thereby inhibiting the disassembly of microtubules, resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein B-cell Leukemia 2 (BCL2). [ ]

Term info

Label

Paclitaxel Ceribate

Synonyms
  • 7beta-((2RS)-2,3-dihydroxypropoxycarbonyloxy)-1-hydroxy-9-oxo-5beta,20-epoxytax-11-ene-2alpha,4,10beta,13alpha-tetrayl 4,10-diacetate 2-benzoate 13-((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoate)
  • PACLITAXEL CERIBATE
  • Paclitaxel Ceribate
Subsets

NCIT_C63923, NCIT_C128784, NCIT_C157711, NCIT_C157712

CAS Registry

186040-50-6

Chemical Formula

C51H57NO18

FDA UNII Code

B3C86E80A0

Has Target

http://purl.obolibrary.org/obo/NCIT_C17219

Preferred Name

Paclitaxel Ceribate

Semantic Type

Pharmacologic Substance, Organic Chemical

UMLS CUI

C3273125

code

C96934