Terminology Service for NFDI4Health
FNBP1 wt Allele
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http://purl.obolibrary.org/obo/NCIT_C97541
Human FNBP1 wild-type allele is located in the vicinity of 9q34 and is approximately 156 kb in length. This allele, which encodes formin-binding protein 1, is involved in both actin remodeling and endocytosis. A chromosomal translocation t(9;11)(q34;q23) of this gene and the MLL gene is associated with rare cases of acute myelogenous leukemia. [ ]
Term info
Label
FNBP1 wt Allele
Synonyms
- FBP17
- FNBP1 wt Allele
- Formin Binding Protein 1 wt Allele
- KIAA0554
- MGC126804
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
A complex chromosomal aberration ins(11;9)(q23;q34)inv(11)(q13q23) fuses the FNBP1 gene and the MLL gene and is associated with rare cases of acute myelogenous leukemia. (Proc Natl Acad Sci U S A. 2001; 98:8756-8761.)
Display Name
FNBP1 wt Allele
EntrezGene ID
23048
GenBank Accession Number
AB011126
OMIM Number
606191
Preferred Name
FNBP1 wt Allele
Semantic Type
Gene or Genome
UMLS CUI
C3273478
code
C97541