Terminology Service for NFDI4Health
COL1A1/PDGFB Fusion Protein
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http://purl.obolibrary.org/obo/NCIT_C99197
A fusion protein encoded by the COL1A1/PDGFB fusion gene. This protein is comprised of various portions of the collagen alpha-1(I) chain protein fused to all but the first 21 amino acids of the platelet-derived growth factor subunit B protein. [ ]
Term info
Label
COL1A1/PDGFB Fusion Protein
Synonyms
- COL1A1-PDGFB Fusion Protein
- COL1A1/PDGFB Fusion Protein
- Collagen Alpha-1(I) Chain/Platelet-Derived Growth Factor Subunit B Fusion Protein
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Mutagenesis experiments demonstrated that COL1A1/PDGFB fusion gene expressing cells produced COL1A1/PDGFB precursors chains, which formed dimers and were processed to give active 30 kDa PDGFB-like dimers. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
Display Name
COL1A1/PDGFB Fusion Protein
Preferred Name
COL1A1/PDGFB Fusion Protein
Related To Genetic Biomarker
http://purl.obolibrary.org/obo/NCIT_C18278, http://purl.obolibrary.org/obo/NCIT_C29949
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C1438340
code
C99197