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FUS/ERG Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C99281

A fusion gene that results from a chromosomal translocation t(16;21)(p11;q22) which fuses the FUS gene with the ERG gene. This rearrangement is associated with acute myeloid leukemia. [ ]

Term info

Label

FUS/ERG Fusion Gene

Synonyms
  • ERG/FUS Fusion Gene
  • FUS-ERG Fusion Gene
  • FUS/ERG Fusion Gene
  • TLS-ERG Fusion Gene
  • TLS/ERG
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

There are at least 3 variants for the FUS/ERG gene. They result from the fusion of the first six or seven exons of the FUS gene to exon 9 of the ERG gene or the fusion of the first eight exons of the FUS gene to exon 7 of the ERG gene. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)

Display Name

FUS/ERG Fusion Gene

Preferred Name

FUS/ERG Fusion Gene

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C91852, http://purl.obolibrary.org/obo/NCIT_C18139

Semantic Type

Gene or Genome

UMLS CUI

C3887934

code

C99281