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BCR/FGFR1 Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99312

A fusion protein encoded by the BCR/FGFR1 fusion gene. This protein is comprised of the coiled-coil domain and Grb2 binding site of breakpoint cluster region protein followed by the tyrosine kinase domains of the basic fibroblast growth factor receptor 1. [ ]

Term info

Label

BCR/FGFR1 Fusion Protein

Synonyms
  • BCR-FGFR1 Fusion Protein
  • BCR/FGFR Fusion Protein
  • BCR/FGFR1 Fusion Protein
  • Breakpoint Cluster Region Protein/Basic Fibroblast Growth Factor Receptor 1 Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The BCR/FGFR1 fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

BCR/FGFR1 Fusion Protein

Preferred Name

BCR/FGFR1 Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C18455, http://purl.obolibrary.org/obo/NCIT_C19929

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3274674

code

C99312