Terminology Service for NFDI4Health

BCR/PDGFRA Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99314


A fusion protein encoded by the BCR/PDGFRA fusion gene. This protein is comprised of the N-terminal oligomerization domain of the breakpoint cluster region protein fused to the C-terminal intracellular domain of the alpha-type platelet-derived growth factor receptor precursor protein, including the tyrosine kinase domains. [ ]

Term info

Label

BCR/PDGFRA Fusion Protein

Synonyms
  • BCR-PDGFRA Fusion Protein
  • BCR/PDGFRA Fusion Protein
  • Breakpoint Cluster Region Protein/Alpha-Type Platelet-Derived Growth Factor Receptor Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The BCR/PDGFRA fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

BCR/PDGFRA Fusion Protein

Preferred Name

BCR/PDGFRA Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C18455, http://purl.obolibrary.org/obo/NCIT_C24666

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3274675

code

C99314