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MLL/MLLT1 Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C99321

A fusion gene that results from a chromosomal translocation t(11;19)(q23;p13.3) which fuses the 5' half of the MLL gene to most of the MLLT1 gene. This rearrangement is associated with acute lymphocytic leukemia and other leukemia types. [ ]

Term info

Label

MLL/MLLT1 Fusion Gene

Synonyms
  • KMT2A-MLLT1 Fusion Gene
  • KMT2A/MLLT1 Fusion Gene
  • MLL-ENL Fusion Gene
  • MLL-MLLT1 Fusion Gene
  • MLL/ENL Fusion Gene
  • MLL/MLLT1 Fusion Gene
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The presence of this fusion gene is associated with a poor prognosis.

Display Name

MLL/MLLT1 Fusion Gene

Preferred Name

MLL/MLLT1 Fusion Gene

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C24601, http://purl.obolibrary.org/obo/NCIT_C18585

Semantic Type

Gene or Genome

UMLS CUI

C3274679

code

C99321