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MLL/MLLT4 Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C99351

A fusion gene that results from a chromosomal translocation t(6;11)(q27;q23) which fuses the 5' half of the MLL gene to most of the MLLT4 gene. This rearrangement is associated with acute myeloid leukemia. [ ]

Term info

Label

MLL/MLLT4 Fusion Gene

Synonyms
  • AF6/MLL Fusion Gene
  • KMT2A-AFDN Fusion Gene
  • KMT2A/AFDN Fusion Gene
  • MLL-AF6 Fusion Gene
  • MLL-MLLT4 Fusion Gene
  • MLL/AF6 Fusion Gene
  • MLL/MLLT4 Fusion Gene
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The presence of this fusion gene is associated with a poor prognosis.

Display Name

MLL/MLLT4 Fusion Gene

Preferred Name

MLL/MLLT4 Fusion Gene

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C24604, http://purl.obolibrary.org/obo/NCIT_C18585

Semantic Type

Gene or Genome

UMLS CUI

C1834588

code

C99351