Terminology Service for NFDI4Health
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NPM1/ALK Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99362

A fusion protein (680 aa, ~75 kDa) that is encoded by the NPM1/ALK fusion gene. This protein contains the N-terminal domain from the nucleophosmin protein and the cytoplasmic domain of the ALK tyrosine kinase receptor protein. [ ]

Term info

Label

NPM1/ALK Fusion Protein

Synonyms
  • NPM-ALK Fusion Protein
  • NPM/ALK Fusion Protein
  • NPM1-ALK Fusion Protein
  • NPM1/ALK Fusion Protein
  • Nucleophosmin/ALK Tyrosine Kinase Receptor Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The NPM1/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

NPM1/ALK Fusion Protein

Preferred Name

NPM1/ALK Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C38184, http://purl.obolibrary.org/obo/NCIT_C21185

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C0541106

code

C99362