Terminology Service for NFDI4Health
RARA/ZBTB16 Fusion Protein
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http://purl.obolibrary.org/obo/NCIT_C99373
A fusion protein encoded by the RARA/ZBTB16 fusion gene. This protein is comprised of the N-terminal transcriptional activation domain of the retinoic acid receptor alpha protein fused to the seven C-terminal zinc fingers of zinc finger and BTB domain-containing protein 16. [ ]
Term info
Label
RARA/ZBTB16 Fusion Protein
Synonyms
- RARA-PLZF Fusion Protein
- RARA-ZBTB16 Fusion Protein
- RARA/PLZF Fusion Protein
- RARA/ZBTB16 Fusion Protein
- Retinoic Acid Receptor Alpha/Zinc Finger and BTB Domain-Containing Protein 16 Fusion Protein
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
Due the alternative splicing of the RARA gene, two forms of the RARA/ZBTB16 fusion protein can be detected: RARA/ZBTB16 Isoform A1 (277 amino acids; ~31 kDa) or RARA/ZBTB16 Isoform A2 (274 amino acids; ~31 kDa) is comprised of either the A1 or A2 transcriptional activation domain of the retinoic acid receptor alpha protein, respectively. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
Display Name
RARA/ZBTB16 Fusion Protein
Preferred Name
RARA/ZBTB16 Fusion Protein
Related To Genetic Biomarker
http://purl.obolibrary.org/obo/NCIT_C28635, http://purl.obolibrary.org/obo/NCIT_C21571
Semantic Type
Amino Acid, Peptide, or Protein
UMLS CUI
C3537406
code
C99373