Terminology Service for NFDI4Health
P2RY8/CRLF2 Fusion Gene
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http://purl.obolibrary.org/obo/NCIT_C99389
A fusion gene that results from an intrachromosomal deletion of the pseudoautosomal region 1of Xp22.3 and Yp11.3 which fuses the noncoding exon 1 of the P2RY8 gene to the entire coding region of the CRLF2 gene. This rearrangement is associated with Down syndrome-associated acute lymphoblastic leukemia. [ ]
Term info
Label
P2RY8/CRLF2 Fusion Gene
Synonyms
- CRLF2/P2RY8 Fusion Gene
- P2RY8-CRLF2 Fusion Gene
- P2RY8/CRLF2 Fusion Gene
Subsets
NCIT_C116977, NCIT_C142800, NCIT_C142799
Contributing Source
CTRP
DesignNote
The P2RY8/CRLF2 gene fusion causes aberrant expression of the CRLF2 gene.
Display Name
P2RY8/CRLF2 Fusion Gene
GenBank Accession Number
GQ280263
Preferred Name
P2RY8/CRLF2 Fusion Gene
PubMedID Primary Reference
19838194
Related To Genetic Biomarker
http://purl.obolibrary.org/obo/NCIT_C97430, http://purl.obolibrary.org/obo/NCIT_C97683
Semantic Type
Gene or Genome
UMLS CUI
C3275246
code
C99389