ETV6/JAK2 Fusion Protein
A fusion protein encoded by the ETV6/JAK2 fusion gene. This protein is comprised of the N-terminal half of the transcription factor ETV6 protein, including the pointed domain and the helix-loop-helix oligomerization domain, fused to the C-terminal tyrosine kinase domains of the tyrosine-protein kinase JAK2 protein. [ ]
Term info
ETV6/JAK2 Fusion Protein
- ETV6-JAK2 Fusion Protein
- ETV6/JAK2 Fusion Protein
- TEL/JAK2 Fusion Protein
- Transcription Factor ETV6/Tyrosine-Protein Kinase JAK2 Fusion Protein
NCIT_C116977, NCIT_C142800, NCIT_C142799
CTRP
The helix-loop-helix domain of the transcription factor ETV6 protein may provide a dimerization interface for kinase domain of the tyrosine-protein kinase JAK2, which activates its tyrosine kinase activity. (Atlas of Genetics and Cytogenetics in Oncology and Haematology)
ETV6/JAK2 Fusion Protein
ETV6/JAK2 Fusion Protein
http://purl.obolibrary.org/obo/NCIT_C18312, http://purl.obolibrary.org/obo/NCIT_C24529
Amino Acid, Peptide, or Protein
C1447569
C99417