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RABEP1/PDGFRB Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99592

A fusion protein (1318, ~150 kDa) encoded by the RABEP1/PDGFRB fusion gene. This protein is comprised of 85% of the Rab GTPase-binding effector protein 1, including 3 and a half of the coiled coil domains, fused to the C-terminal transmembrane and cytoplasmic domains of the beta-type platelet-derived growth factor receptor protein, including the protein kinase domain. [ ]

Term info

Label

RABEP1/PDGFRB Fusion Protein

Synonyms
  • RABEP1-PDGFRB Fusion Protein
  • RABEP1/PDGFRB Fusion Protein
  • RABPT5-PDGFRB Fusion Protein
  • RABPT5/PDGFRB Fusion Protein
  • Rab GTPase-Binding Effector Protein 1/Beta-Type Platelet-Derived Growth Factor Receptor Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The RABEP1/PDGFRB fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

RABEP1/PDGFRB Fusion Protein

Preferred Name

RABEP1/PDGFRB Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C24667, http://purl.obolibrary.org/obo/NCIT_C97751

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3274816

code

C99592