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MESDC2/SENP1 Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99746

A fusion protein encoded by the MESDC2/SENP1 fusion gene. This protein is comprised of the signal peptide of the LDLR chaperone MESD protein, fused to all but the first 8 amino acids of the sentrin-specific protease 1 protein, including the nuclear localization and protease domains. [ ]

Term info

Label

MESDC2/SENP1 Fusion Protein

Synonyms
  • LDLR Chaperone MESD/Sentrin-Specific Protease 1 Fusion Protein
  • MESDC2-SENP1 Fusion Protein
  • MESDC2/SENP1 Fusion Protein
  • MESE
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Sentrin-specific protease 1 cleaves SUMO-1 from target proteins. The MESDC2/SENP1 fusion protein retains this activity. (Hum. Mol. Genet. 2005; 14: 1955-1963.)

Display Name

MESDC2/SENP1 Fusion Protein

Preferred Name

MESDC2/SENP1 Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C98087, http://purl.obolibrary.org/obo/NCIT_C98061

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3537413

code

C99746