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SPECC1/PDGFRB Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99834

A fusion protein encoded by the SPECC1/PDGFRB fusion gene. This protein is comprised of almost the entire cytospin-B protein fused to the C-terminal transmembrane and cytoplasmic domains of the beta-type platelet-derived growth factor receptor protein, including the protein kinase domain. [ ]

Term info

Label

SPECC1/PDGFRB Fusion Protein

Synonyms
  • Cytospin-B/Beta-Type Platelet-Derived Growth Factor Receptor Fusion Protein
  • HCMOGT-1/PDGFRB Fusion Protein
  • HCMOGT1-PDGFRB Fusion Protein
  • HCMOGT1/PDGFRB Fusion Protein
  • SPECC1-PDGFRB Fusion Protein
  • SPECC1/PDGFRB Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The SPECC1/PDGFRB fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

SPECC1/PDGFRB Fusion Protein

Preferred Name

SPECC1/PDGFRB Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C24667, http://purl.obolibrary.org/obo/NCIT_C97531

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3274993

code

C99834