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FGFR1OP2/FGFR1 Fusion Gene

Go to external page http://purl.obolibrary.org/obo/NCIT_C99835

A fusion gene that results from a chromosomal insertion ins(12;8)(p11;p11p22) that fuses exon 4 of the FGFR1OP2 gene with exon 9 of the FGFR1 gene. This translocation is associated with 8p11 myeloproliferative disorder. [ ]

Term info

Label

FGFR1OP2/FGFR1 Fusion Gene

Synonyms
  • FGFR1/FGFR1OP2 Fusion Gene
  • FGFR1OP2-FGFR1 Fusion Gene
  • FGFR1OP2/FGFR1 Fusion Gene
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

Since the direction of FGFR1OP2 transcription is in the opposite orientation to the direction of FGFR1 transcription, an inversion must have taken place during the formation of the chimeric gene. (OMIM)

Display Name

FGFR1OP2/FGFR1 Fusion Gene

Preferred Name

FGFR1OP2/FGFR1 Fusion Gene

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C98075, http://purl.obolibrary.org/obo/NCIT_C19929

Semantic Type

Gene or Genome

UMLS CUI

C1851030

code

C99835