Terminology Service for NFDI4Health

FGFR1OP2/FGFR1 Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99836


A fusion protein (526 aa, ~60 kDa) encoded by the FGFR1OP2/FGFR1 fusion gene. This protein is comprised of the first 2 coiled-coil domains of the FGFR1 oncogene partner 2 protein followed by the tyrosine kinase domains of the basic fibroblast growth factor receptor 1. [ ]

Term info

Label

FGFR1OP2/FGFR1 Fusion Protein

Synonyms
  • FGFR1 Oncogene Partner 2/Basic Fibroblast Growth Factor Receptor 1 Fusion Protein
  • FGFR1OP2-FGFR1 Fusion Protein
  • FGFR1OP2/FGFR1 Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The FGFR1OP2/FGFR1 fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

FGFR1OP2/FGFR1 Fusion Protein

Preferred Name

FGFR1OP2/FGFR1 Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C98075, http://purl.obolibrary.org/obo/NCIT_C19929

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3274994

code

C99836