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NCOA4/RET Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99848

A fusion protein encoded by the NCOA4/RET fusion gene. This protein is comprised of approximately 240 N-terminal amino acids of the nuclear receptor coactivator 4 protein, fused with most of the C-terminal cytoplasmic domain of the proto-oncogene tyrosine-protein kinase receptor Ret protein, including the tyrosine kinase domain. [ ]

Term info

Label

NCOA4/RET Fusion Protein

Synonyms
  • ELE1-RET Fusion Protein
  • ELE1/RET Fusion Protein
  • NCOA4-RET Fusion Protein
  • NCOA4/RET Fusion Protein
  • Nuclear Receptor Coactivator 4/Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Fusion Protein
  • PTC3 Chimeric Oncoprotein
  • RET/NCOA4 Oncoprotein
  • RFG-RET Fusion Protein
  • RFG/RET Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The NCOA4/RET fusion protein is a constitutively activated tyrosine kinase.

Display Name

NCOA4/RET Fusion Protein

Preferred Name

NCOA4/RET Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C18257, http://purl.obolibrary.org/obo/NCIT_C18381

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3275000

code

C99848