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RNF213/ALK Fusion Protein

Go to external page http://purl.obolibrary.org/obo/NCIT_C99870

A fusion protein (680 aa, ~75 kDa) that is encoded by the RNF213/ALK fusion gene. This protein contains 1172 N-terminal amino acids of protein ALO17 fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein. [ ]

Term info

Label

RNF213/ALK Fusion Protein

Synonyms
  • ALO17-ALK Fusion Protein
  • ALO17/ALK Fusion Protein
  • Protein ALO17/ALK Tyrosine Kinase Receptor Fusion Protein
  • RNF213-ALK Fusion Protein
  • RNF213/ALK Fusion Protein
  • Ring Finger Protein 213/ALK Tyrosine Kinase Receptor Fusion Protein
Subsets

NCIT_C116977, NCIT_C142800, NCIT_C142799

DesignNote

The RNF213/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.

Display Name

RNF213/ALK Fusion Protein

Preferred Name

RNF213/ALK Fusion Protein

Related To Genetic Biomarker

http://purl.obolibrary.org/obo/NCIT_C38184, http://purl.obolibrary.org/obo/NCIT_C97390

Semantic Type

Amino Acid, Peptide, or Protein

UMLS CUI

C3275009

code

C99870